Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research.

Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research.

Annu Rev Entomol. 2012 Oct 15;

Authors: Yamanaka N, Rewitz KF, O'Connor MB

Abstract
The steroid hormone ecdysone is the central regulator of insect developmental transitions. Recent new advances in our understanding of ecdysone action have relied heavily on the application of Drosophila melanogaster molecular genetic tools to study insect metamorphosis. In this review, we focus on three major aspects of Drosophila ecdysone biology: (a) factors that regulate the timing of ecdysone release, (b) molecular basis of stage- and tissue-specific responses to ecdysone, and (c) feedback regulation and coordination of ecdysone signaling. Expected final online publication date for the Annual Review of Entomology Volume 58 is December 03, 2013. Please see http://www.annualreviews.org/catalog/pubdates.aspx for revised estimates.

PMID: 23072462 [PubMed - as supplied by publisher]

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