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Lochmolins A-G, new sesquiterpenoids from the soft coral Sinularia lochmodes.
Mar Drugs. 2012 Jul;10(7):1572-81
Authors: Tseng YJ, Shen KP, Lin HL, Huang CY, Dai CF, Sheu JH
Abstract
Seven new sesquiterpenoids, lochmolins A-G (1-7), were isolated from a Taiwanese soft coral Sinularia lochmodes. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds 1-4 were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells.
PMID: 22851927 [PubMed - indexed for MEDLINE]
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